When Nature Is Not Enough
    When Nature Is Not Enough

    IVF will hopefully bring us the miracle we are waiting for.

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    About Me

    Name: Liz
    Location: New York

    I'm 37 and have been happily married since Sept. 2002. Ivan is truly my companion in life. Our TTC journey has felt like a never ending roller coaster ride. We had an ectopic PG in Dec. 04 and in April 05 found out my IF is due to tubal abnormality. We were told IVF was our only hope. July 05 we did IVF # 1 and it was a chemical PG. We did IVF # 2 in Oct. 05 and it was a BFN. In Jan. 06 we did a combined fresh and frozen embryo transfer and it was a BFN. We were determined not to give up our dream of having a baby. IVF # 4 was in April 06. The cycle worked like a charm and on December 20, 2006 we were blessed with Hannah and Matthew.

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    Friday, March 17, 2006

    Calendar/Protocol

    AF finally arrived on Tuesday and yesterday I started BCP. I received my calendar...boy will I be on lots of meds.

    For those that had wanted to know the protocol here it is. SIRM refers to it as the Agonist/Antagonist Conversion Protocol.

    BCP 3/16 - 4/7
    Lupron 10 units from 4/3 - 4/7; 5 units 4/8 - 4/10
    Dexamethosone (corticosteroid) starts on 4/3 until I am told to stop. If I'm PG I continue.
    4/11 - Baseline u/s and E2
    Ganirelex 125 mcg - 4/11 - stop when I trigger
    Follistim 450 units - 4/14 - 4/16; 300 units 4/17 - until I trigger
    Luveris 1 vial - 4/17 - until I trigger

    At the onset of menstruation that follows the initiation of GnRH agonist (Lupron) I begin low dose antagon (Ganirelex). Luveris (recombinant LH) is administered 4-6 days following initiation of gonadotropin stimulation (Follistim).

    ** Ganirelix is administered after the lupron to maintain the inhibition of ovulation while minimizing the extra suppression that can be seen with prolonged lupron. They dose the ganirelix differently as well, and give it at 1/2 the usual dose, and give it continuously through the stimulation. The lower dose also helps to maximize on stimulation while assuring the prevention of premature ovulation. When Luveris is started 4-6 days after stimulation, it is done to add LH to the cycle after initial stimulation with FSH alone, similar to what is occuring in natural cycles. Some LH is necessary for maximal stimulation, but they want to avoid too much LH, which can be detrimental. Luveris is a new form of pure LH- either that or Repronex is used during stimulation to add the LH.

    I will also be on:
    Clindamycin - suppository antibiotic
    Tequin - oral antibiotic

    After ER:

    E2V 1mg/Prog 50mg Vag Supp
    Progesterone in Olive Oil.

    I can't wait to start. Can't say I'm hopeful but eager to just start and "get it over with"...not the best attitude but that's for another post.


    | posted by Liz at 7:22 PM |


    18 Comments:

    Anonymous Anonymous commented at 10:54 PM~  

    I've been looking forward to seeing what your protocol is. I've been reading on different protocols and when to administer meds and it seems your doctor is very thorough and efficient. I printed your protocol and will discuss it with my RE. Wishing you the best...you've officially started.

    Anonymous Anonymous commented at 9:52 AM~  

    Hoping the change in protocol is the difference and you get your BFP.

    Thanks for the article about the protocol.

    Lots of luck to you!!!

    Anonymous Anonymous commented at 12:05 PM~  

    Good luck with your cycle. It's great that you will be cycling with SIRM...Dr. Sher is the BEST!!!!!

    Anonymous Anonymous commented at 12:52 PM~  

    Looks like a very tailored protocol, I do hope it does the trick. Do you know the rationale for each part of it?

    Blogger Lut C. commented at 6:36 PM~  

    I too really want to get it all over with. If none of this is going to work, I want to find out asap. There's no point in dragging it out.

    Good luck with this cycle.

    Anonymous Anonymous commented at 1:13 PM~  

    I know how hard it is to have a positive attitude. The protocol seems very thorough. Wishing you the best with this cycle.

    Anonymous Anonymous commented at 1:58 PM~  

    Good luck with this new protocol. I hope it does the trick.

    Blogger Krista commented at 4:35 PM~  

    Thanks for the comments on my post. I wish you the best of luck with this cycle. I know what you mean by wanting to get it over with. I find that far too often hope springs up inside when you least want it too and then you are extra disappointed in the end. It's sad that we have gotten far enough to feel that way.

    Blogger Liz commented at 9:17 PM~  

    Thalia, I updated the post to explain the rationale for the timing of each med.

    Anonymous Anonymous commented at 10:12 PM~  

    I will be talking to my RE about my future protocol. Wishing you the very best with this new cycle.

    I totally understand you wanting to get it over with. Sending positive vibes your way.

    Blogger Sporty commented at 9:57 AM~  

    All the best of luck to you with this cycle Liz. I have to say that I admire everything that you are doing. You are a strong person and you deserve to be happy!

    Take care and thinking of you!
    Chasity

    Blogger x commented at 1:58 PM~  

    Getting started is the best part. It sounds like you are with a great clinic. All the best, you deserve it!!!

    Blogger Linda commented at 2:05 PM~  

    Sorry it's been a while since I dropped by. I love the new format!

    I misread the last part of your post and thought "Tequin" said "tequila." That's my kind of protocol!

    Good luck with it all. I will be rooting for you.

    Blogger Jenn commented at 3:53 PM~  

    Wow - that is intense. I am praying that this is it - Good luck to you Liz!

    Take Care,
    Jenn

    Anonymous Anonymous commented at 9:43 PM~  

    That protocol is very thorough. I've been reading up on SIRM...they seem great! Wishing you the best!!

    Anonymous Anonymous commented at 10:03 PM~  

    Thanks for posting your protocol. Will discuss it with my RE. Hoping this cycle is it for you!

    Blogger Ally commented at 8:27 AM~  

    Good Luck with this cycle Liz...sorry there are so many meds to take.

    I'll be thinking about ya.

    Take care.

    Anonymous Anonymous commented at 9:01 AM~  

    Wow that's alot of meds...very thorough protocol. I like the explanation about the timing.

    Wishing you the best with the cycle.

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